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COMPOSITION:
Each vial contains:
Procaine Penicillin........ 3MIU
Penicillin Sodium....... 1 MIU
DESCRIPTION:
White or almost white sterile powder.
PHARMACOLOGICAL:
This preparation is available in the form of a sterile dry powder containing benzyl
penicillin sodium and procaine penicillin with suitable amount of
suspending and buffering agents. The advantage of such a preparation is
that it can exert both the prompt action due to the high initial blood
levels produced by the soluble potassium salt, and the prolonged action
of the insoluble procaine penicillin salt, which is absorbed and
excreted slowly.
Therefore a single dose injection of this preparation can maintain an effective concentration in blood for 12-24 hours.
INDICATIONS:
It has the same indications as penicillin. As its peak blood concentration is relatively low,
it is only indicated in mild infections caused by penicillin-sensitive
bacteria, such as tonsillitis, scarlet fever, erysipelas, furuncles and
carbuncles. It is also effective for syphilis, Vincent's angina and
gonorrhea.
DOSAGE AND ADMINISTRATION:
It is given by I.M. injection only.
A suitable amount of water for injection is added into the vial before use. 500,000 IU-1,000,000IU each time ,once or twice a day.
CAUTION:
Before administration, skin tests of procaine and penicillin should be made. It should not
be administrated to patients hypersensitive to penicillin and
procaine.
STORAGE:
Kept in well-closed containers and stored in a dry place
RECOMMENDED SHELF LIFE:
Three years
PACKING:
In vials of 4,000,000 IU-each containing 3,000,000 IU of procaine penicillin and l,000,000 IU of penicillin sodium.
20ml,32ml per vial. 50 vials/box; 600 vials/carton.